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CAPE Biology Unit 1 · 2015 · Paper 2 · Question 5(a)

Explain what is meant by the term 'gene'. Outline the principles of using restriction enzymes to cut a gene from a length of DNA. Note: Details of the steps involved in recombinant DNA technology are not required.

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  1. 5(b)Gene therapy is the application of the principle of genetic engineering in the treatment of diseases.[1 mark]
  2. 5(b)(i)Give a brief description of one human disease for which the use of somatic gene therapy has been shown to be effective.[2 marks]
  3. 5(b)(ii)Discuss FOUR reasons why somatic gene therapy, despite its potential, is still not used as an effective treatment for human diseases.[8 marks]

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