CAPE Biology Unit 1 · 2007 · Paper 1 · Question Q35
In the hereditary disease, sickle-cell anaemia, the amino acid, glutamic acid, found in normal haemoglobin, is substituted at a particular location by the amino acid valine. The codon for glutamic acid is GAA. The codons for valine can be either GUU, GUC or GUA. One single base alone is changed during the mutation. Which of the following would be the corresponding DNA nucleotide responsible for the change?
- (A)CAA
- (B)CAT
- (C)CAU
- (D)CAG
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