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CAPE Biology Unit 1 · 2013 · Paper 2 · Question 5(a)(ii)

Mycobacterium tuberculosis, the bacterium that causes tuberculosis, has been virtually eliminated by the widespread use of two effective antibiotics. Due to the development of antibiotic-resistant strains of the bacterium, the disease has re-emerged as a major public health problem.

Briefly comment on why mutation is regarded as a driving force of evolution.

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  1. 5(a)(i)Applying Darwin's theory of evolution by natural selection, discuss how resistance to antibiotics could have evolved in bacteria. Include in your discussion a…[6 marks]
  2. 5(b)Define the term 'speciation', and using examples, explain how geographical isolation may lead to speciation.[7 marks]

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