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2 marksImmunology

CAPE Biology Unit 2 · 2003 · Paper 1 · Question 7(a)

In Severe Combined Immunodeficiency (SCID), a defective gene prevents the synthesis of adenine deaminase critical for immune function. A retrovirus containing the functional gene can be used to modify cells of newborns.

Name the type of therapy mentioned in the passage and explain what effect it would have on the newborn baby.

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Other parts of this question

  1. 7(b)A mother whose first child died of SCID asks during her second pregnancy to check the foetus. Name ONE method which the doctor could use to determine if the…[1 mark]
  2. 7(c)In SCID disorder, stem cells are isolated, genetically modified, and re-injected. Give ONE other method by which genetically modified genes can be introduced…[1 mark]
  3. 7(d)(i)Outline THREE ways in which the government can determine if the genetically modified maize has contaminated the indigenous maize.[4 marks]
  4. 7(d)(ii)If the indigenous maize has been contaminated by the genetically modified maize, deduce how the genotype could have been affected.[1 mark]
  5. 7(d)(iii)How can the original genotype of the indigenous maize be restored?[1 mark]

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