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5 marksCell Division and Variation

CAPE Biology Unit 1 · 2015 · Paper 2 · Question 2(b)

Explain how 'substitution' and 'insertion' result in genetic variation. Discuss how gene mutation causes sickle-cell anaemia.

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  1. 2(a)Figure 3 is a diagram of a cell with four chromosomes (haploid number = 2) during the process of meiosis.[1 mark]
  2. 2(a)(i)Name the stage of meiosis illustrated in Figure 3.[1 mark]
  3. 2(a)(ii)In the boxes below, make labelled sketches to illustrate the next TWO key stages of meiosis in this cell. Write the name of the stages on the lines provided…[6 marks]
  4. 2(a)(iii)Explain how the key stages identified in (a)(i) and (ii) contribute to genetic variation.[3 marks]

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